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Paradigm Shift In Alzheimer's Research


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Geplaatst op 16 oktober 2007 - 16:00

Groundbreaking new discoveries have opened the door for a new and better understanding of Alzheimer's disease, as one of the most important future public health challenges. Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by extensive neuronal degeneration and the development of neuritic amyloid plaques and neurofibrillary tangles. Neuronal and synaptic losses in AD are correlated with dementia and occur in specific brain areas involved in memory processing. Long-standing evidence shows that progressive cerebral deposition of A plays a seminal role in the pathogenesis of AD.

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