Dankjewel. Met gebruik van de Engelse term kom ik enkele interessante artikelen tegen.
IQR = inter-quartile range = range between 25% and 75% percentile.
Definities volgens
Medical Dictionary:
- Forced vital capacity (FVC) is the total amount of air a person can exhale forcibly after maximal inhalation.
- Forced expiratory volume (FEV) is the volume that can be exhaled from a full inhalation by exhaling as forcefully and rapidly as possible for a timed period. Times are denoted by subscripts, such as FEV0.5, FEV1.0, FEV2.0, and FEV3.0 for FEV values for 0.5, 1, 2, and 3 seconds.
- Forced expiratory flow (FEF) is the rate of airflow recorded in measurements of forced vital capacity, usually calculated as an average flow over a given portion of the expiratory curve; the portion between 25 and 75 percent of forced vital capacity is called the maximal midexpiratory flow. Called also forced expiratory flow rate.
In
dit artikel in Nature (2019) staat de volgende conclusie.
An IQR (10 μg/m3) increase in PM2.5 decreased FVC by 106.38 ml (4.47%), while an IQR (7.29 μg/m3) increase in PM2.5–10 decreased FEV1 and FEF25–75% by 91.23 ml (4.85%) and 104.44 ml/s (5.58%), respectively.
Oftewel: hoe hoger de concentratie ultrafijnstof, hoe kleiner de longinhoud. Deze algemene conclusie wordt ook beschreven in
dit artikel van The Lancet Planetary Health (2018), maar met veel grotere onnauwkeurigheid.
In
dit artikel in J Am Heart Assoc. (2018) staat de volgende conslusie.
The concentration-response relationship between PM2.5 and hypertension was nonlinear, with a threshold concentration of 47.9 μg/m3. The odds ratio of hypertension related to a 10-μg/m3 increase in PM2.5 above threshold was 1.010. A 10-μg/m3 increase in PM2.5 above threshold corresponded to a 0.569 mm Hg elevation in systolic blood pressure and a 0.384 mm Hg elevation in diastolic blood pressure. There were 2.3% of the hypertension cases that could be attributed to PM2.5 exposures in reproductive-age adult populations.
Oftewel: Boven een krititische concentratie ultrafijnstof geldt: hoe hoger de concentratie ultrafijnstof, hoe hoger de bloeddruk.
In
dit artikel in American Journal of Respiratory and Critical Care Medicine (2017) staat de volgende conclusie.
Exposure to coarse PM was associated with increased asthma diagnosis prevalence (rate ratio [RR] for 1-μg/m3 increase in coarse PM level, 1.006; hospitalizations (RR, 1.023), and emergency department visits (RR, 1.017) when adjusting for fine PM.
Oftewel: Hoe hoger de concentratie ultrafijnstof, hoe hoger het aantal astma-aanvallen.
Mijn eigen conclusie hieruit is dat er een kleine, maar significante correlatie is tussen ultrafijnstof en gezondheidsproblemen.
